Plant based sleep gummies are certainly a safe alternative to conventional sleep aids. However, just because something is natural doesn't mean you shouldn't use caution. Plant based sleep gummies, like all things, should be used in moderation. Some supplements can interact with medications and have unanticipated side effects. For instance, CBD is used in some plant based sleep aids. The reason being, CBD has been shown to effectively treat insomnia. However, a 2019 study done on mice did raise some safety concerns about CBD’s potential for liver damage and its interactions with other medications.